The present work details viscoplasticity, especially by choosing products that are known to present little viscoelasticity. Full paper available in the PAPERS section.

Find others papers here and learn about

• Characterization of the viscoelasticity of pharmaceutical tablets using impulse excitation technique
  
• Tablet formulation development focusing on the functional behaviour of water uptake and swelling
  
• Characterization and modeling of the viscoelasticity of pharmaceutical tablets
  

MySTYL'One users exclusive!

We're inviting you to chat with Calvin Sun Changquan and Gerrit Vreeman from University of Minnesota on Air entrapment during tablet compression - Diagnosis, impact on tableting performance, and mitigation strategies on Wednesday, May 24th @4:30pm Paris time.

Calvin Sun and Gerrit have published in the International Journal of Pharmaceutics and have studied the role of air entrapment during tablet compression using a compaction simulator. The impact of air entrapment...

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The present work details a model based on the Ryshkewitch-Duckworth equation that can estimate the compactibility profiles of lubricated formulations. Available model showing extended quantitative predictive accuracy for the influence of lubricant concentration on the mechanical strength of tablets. Full paper available in the PAPERS section.

Find others papers here and learn about

• Effect of binder type and lubrication method on the binder efficacy for direct compression
  
• Evaluation of an externa...

The present work details an in-depth understanding of the functional behaviour of the tablet material, composition and structural properties under in vivo-like hydrodynamic forces regarding disintegration and the temporal progress of dispersion. Full paper available in the PAPERS section.

Find others papers here and learn about

• Pharmaceutical Development of Film-Coated Mini-Tablets with Losartan Potassium for Epidermolysis Bullosa
  
• Tablet formulation development focusing on the functional behavio...

The present work details powder compaction simulations, using the finite element method (FEM) in combination with the density-dependent Drucker-Prager Cap model, which can be used to aid the design process of pharmaceutical tablets. Full paper available in the PAPERS section.

Find others papers here and learn about

• Breaking patterns of press-coated tablets during the diametral compression test: Influence of the product, geometry and process parameters
• Novel ultrasonic in-die measurements during ...

The present work in mechanistic process modeling presents an opportunity to reduce experimental burden, enabling relationships between process parameters and product attributes to be mapped out using in-silico experiments. Full paper available in the PAPERS section.

Find others papers here and learn about

• Investigating key properties of model excipients and binary powder blends using ultrasonic in-die measurements on a compaction simulator 
• Impact of Incorporated Drugs on Material Properties of ...

MySTYL'One user exclusive!

New bulletin available on the methodology of MEDELPHARM Science Lab to study the effects of granulation critical process parameters on product quality attributes. A development of a new directcompression grade of excipient produced by granulation. 

The present work compares the in-die elastic recovery profiles with and without precompression prior to the main compression of celecoxib powder. Full paper available in the PAPERS section.

Find others papers here and learn about

• Lamination of pharmaceutical tablets: Classification and influence of process parameters
• Characterization and modeling of the viscoelasticity of pharmaceutical tablets
• Unravelling capping issues using STYL'One dwell time or punch speed