Keep up with the latest in the tableting community!
May 10, 2023
This work summarizes the findings from the collection of DPC parameters from 60 materials. From this dataset several important conclusions can be drawn about typical and extreme behaviors of formulations and excipients. From these findings key signals of program risk can be determined and utilized early in the formulation development process to avoid costly manufacturing and scale-up issues.
The paper is available in the PAPERS section.
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#finite elements methods #STYL'One #compaction #Drucker-Prager Cap model #DPC
April 28, 2022
The present work details powder compaction simulations, using the finite element method (FEM) in combination with the density-dependent Drucker-Prager Cap model, which can be used to aid the design process of pharmaceutical tablets. Full paper available in the PAPERS section.
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#formulation #Predictive modelling #mechanical properties #Mixing model #Powder compaction #STYLOne #Drucker-Prager Cap model