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Showing posts tagged as : #STYL'One

Announcement

MySTYL'One

March 13, 2023

The Assessment of the Capping Tendency of the Tablet during The Pharmaceutical Tabletting Using Finite Element Analysis in Computational Modelling Tools

In this paper you will find a study that focuses on the assessment of the capping problem using computer modelling of the pharmaceutical powder compression and consolidation process using the finite element analysis (FEA) method implementing the Drucker–Prager Cap (DPC) model. The paper is available in the PAPERS section.

Find others papers here and learn about

  • Characterization of Tableting Speed-Dependent Deformation Properties of Active Pharmaceutical Ingredients in Powder Mixtures Using Out-...

In this paper you will find a study that focuses on the assessment of the capping problem using computer modelling of the pharmaceutical powder compression and consolidation process using the finite element analysis (FEA) method implementing the Drucker–Prager Cap (DPC) model. The paper is available in the PAPERS section.

Find others papers here and learn about

  • Characterization of Tableting Speed-Dependent Deformation Properties of Active Pharmaceutical Ingredients in Powder Mixtures Using Out-of-Die Method
  • Influence of the unloading conditions on capping and lamination: Study on a compaction simulator
  • Shear strength of pharmaceutical tablets: Theoretical considerations, evaluation and relation with the capping tendency of biconvex tablets

#STYL'One #Powder compaction #Drucker-Prager Cap model #capping

Announcement

MySTYL'One

Feb. 20, 2023

Resolving Tableting Challenges And Optimization Of The Tablet Compression Step Of An Immediate-Release Analgesic Formulation

MySTYL'One user exclusive!

This new bulletin available details a study on an optimization of the tablet compression process of an immediate-release analgesic formulation.

#analgesic formulation #compression properties #STYL'One #process

Announcement

MySTYL'One

Feb. 15, 2023

Tablet Disintegratability: Sensitivity of Superdisintegrants to Temperature and Compaction Pressure

In this paper you will find a study that investigated the effects of temperature and compaction pressure on tablet disintegratability to gain deeper insights into superdisintegrant sensitivity and function. The paper is available in the PAPERS section.

Find others papers here and learn about

  • Downstream processing of amorphous solid dispersions into orodispersible tablets
  • Upscaling of external lubrication from a compaction simulator to a rotary tablet press
  • Screening of lubricants towards their ap...

In this paper you will find a study that investigated the effects of temperature and compaction pressure on tablet disintegratability to gain deeper insights into superdisintegrant sensitivity and function. The paper is available in the PAPERS section.

Find others papers here and learn about

  • Downstream processing of amorphous solid dispersions into orodispersible tablets
  • Upscaling of external lubrication from a compaction simulator to a rotary tablet press
  • Screening of lubricants towards their applicability for external lubrication

#STYL'One #swelling #disintegration tablets #superdisintegrants #stain recovery #temperature #tablet

Announcement

MySTYL'One

June 29, 2022

A generalized image analytical algorithm for investigating tablet disintegration

The University of Copenhagen presents a work on an approach for development of the optimal tablet formulation as well as gaining an understanding on how the selection of excipients and manufacturing processes ultimately influences tablet disintegration.Medelpharm is part of this innovative project. Full paper available in the PAPERS section.

Find others papers here and learn about

  • Modeling of Disintegration and Dissolution Behavior of Mefenamic Acid Formulation Using Numeric Solution of Noyes-W...

The University of Copenhagen presents a work on an approach for development of the optimal tablet formulation as well as gaining an understanding on how the selection of excipients and manufacturing processes ultimately influences tablet disintegration.Medelpharm is part of this innovative project. Full paper available in the PAPERS section.

Find others papers here and learn about

  • Modeling of Disintegration and Dissolution Behavior of Mefenamic Acid Formulation Using Numeric Solution of Noyes-Whitney Equation with Cellular Automata on Microtomographic and Algorithmically Generated Surfaces
  • Predictive selection rule of favourable image processing methods for X-ray micro-computed tomography images of tablets
  • Pharmaceutical Development of Film-Coated Mini-Tablets with Losartan Potassium for Epidermolysis Bullosa

#STYL'One #Tablet disintegration #multivariate data analysis #tablet disintegration kinetics #image analysis #imaging

Announcement

MySTYL'One

April 11, 2022

Physicochemical Changes and Chemical Degradation of Gliclazide during Twin-Screw Melt Granulation

The present work details how the twin-screw melt granulation process affects the chemical stability and process-induced physicochemical changes of the drug. Full paper available in the PAPERS section.

Find others papers here and learn about

  • Structure-property relationship of Amorphous Maltitol as Tableting Excipient
  • Development of Coprocessed Chitin-Calcium Carbonate as Multifunctional Tablet Excipient for Direct Compression
  • Simulations of Drug Realease Profiles as a Function of Different Geometrical Designs

#granulation process #STYL'One #Gliclazide #degradation #kneading element

Announcement

MySTYL'One

April 4, 2022

Pharmaceutical Development of Film-Coated Mini-Tablets with Losartan Potassium for Epidermolysis Bullosa

The present work details the development of an oral solid dosage form to address the rare disease epidermolysis bullosa, which can appear already in newborn children. Full paper available in the PAPERS section.

Find others papers here and learn about

  • Transfer and scale-up of the manufacturing of orodispersible mini-tablets from a compaction simulator to an industrial rotary tablet press
  • QbD approach formulation design for metformin HCI and evaluations
  • Tableting of mini-tablets in comparison with conventionally sized tablets: A comparison of tableting properties and tablet dimensions

#STYL'One #stability #epidermolysis bullosa #losartan potassium #dry granulation #paediatrics #rare disease #mini-tablets #coating

Announcement

MySTYL'One

March 30, 2022

Why Tabletability Assessment Of Your Formulation Is A Fundamental Step Of Your Tablet Development ?

MySTYL'One user exclusive!

New bulletin available on fundamental step in a tablet development. This case study highlight how quickly excipients or powder blends can be compared thanks to tabletability profiles.

#bulletin #formulation #STYL'One #production #tabletability

Announcement

MySTYL'One

Feb. 7, 2022

Granutools Pharma User Club webinar - Replay available

On January 27th, 2022 Granutools organized their User Club Meeting for members of the pharmaceutical sector. 

This virtual meeting was the occasion to hear case studies presented by speakers who use Granutools equipment for their work. 

Delphine Ach-Hubert, formulation scientist at MEDELPHARM, presented case studies on particle size influence on tableting properties, using Granutools equipment and the STYL'One Evo compaction simulator. 

Replay available HERE

#webinar #STYL'One #Granutools #particle size

Feature article

MySTYL'One

Jan. 12, 2022

STYL'One Nano Live Demo


New event open to MySTYL'One members!

Join us for the STYL’One Nano Live Demo!

Wednesday January 19th, 4 pm - 5 pm (Paris Time)

#STYL'One Nano #STYL'One #live demo #online

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