MySTYL'One
March 2, 2023
Get access for this online event replay.
Date: Tuesday, February 28th, 2023
Time: 3pm (Paris time)
Duration: 60 minutes
"Assessing temperature influence on tablet quality attributes - Using a temperature-controlled die on the STYL’One Evo compaction simulator" - by Hanna Grumann, PhD student at the Institute of Pharmaceutics and Biopharmaceutics, Heinrich Heine University Düsseldorf, Germany under the supervision of Prof. Peter Kleinebudde.
#STYL'One evo #compaction simulator #sticking #picking #temperature influence #webinar
Parmaceutical Networking
Feb. 20, 2023
MEDELPHARM’s series of STYL’One tableting instruments provides a range of solutions to industry needs for containment and isolation to provide regulatory compliant levels of operator protection when working with highly potent active pharmaceutical ingredients (HPAPIs).
The need for effective containment solutions has become ever more pressing as increasing focus on small and large molecule synthesis create new classes of high toxicity HPAPIs, with consequent shift in emphasis from protection o...
MEDELPHARM’s series of STYL’One tableting instruments provides a range of solutions to industry needs for containment and isolation to provide regulatory compliant levels of operator protection when working with highly potent active pharmaceutical ingredients (HPAPIs).
The need for effective containment solutions has become ever more pressing as increasing focus on small and large molecule synthesis create new classes of high toxicity HPAPIs, with consequent shift in emphasis from protection of the molecule from cross contamination or deviation from process to prioritization of protection of the environment and workers from contamination by the molecule.
Thermofisher Scientific
Nov. 23, 2022
With the ever-growing pressure to get new therapies to patients faster, predictive modeling and simulation tools are increasingly recognized as critical enabling technologies for accelerating drug product development. In the development of oral solid dosage forms, predictive modeling and simulation tools of the manufacturing processes can enhance process understanding, save on API supply, improve product quality, and reduce or eliminate many of the bottlenecks associated with empirical method...
With the ever-growing pressure to get new therapies to patients faster, predictive modeling and simulation tools are increasingly recognized as critical enabling technologies for accelerating drug product development. In the development of oral solid dosage forms, predictive modeling and simulation tools of the manufacturing processes can enhance process understanding, save on API supply, improve product quality, and reduce or eliminate many of the bottlenecks associated with empirical methods.
Each active pharmaceutical ingredient (API) has its own set of unique physical and chemical properties that can affect the success of product formulations and manufacturing routes. On account of this, the manufacturing process for solid dosage forms need to be thoroughly understood. Determining robust formulations and processes for a given compound requires a deep understanding of material science and powder behavior.
#R&D #STYL'One evo #Powder compaction #science lab #Material science
MySTYL'One
July 22, 2022
The present works demonstrated from a study to predict capping on biconvex tablets from a wide range of products (18 formulations, 8 of which presenting capping), using the properties characterized on defect-free flat-faced tablets (tensile strength, solid fraction, elastic recovery, etc.). The study is available in the PAPERS section.
Find others papers here and learn about
CPhI Global Pharma Events
July 9, 2022
MySTYL'One members exclusive!
CPhI worldwide 2018
Conference in the ICSE theatre : Compression Simulation as a Powerful Quality by Design (QbD) Tool
Animated by Aline Moulin, Senior Project Manager - Pharmaceutical Development
#STYL'One evo #scale-up #optimization #QbD #compaction simulator #conference #prototype
MySTYL'One
June 2, 2022
MySTYL'One user exclusive!
New bulletin available on the methodology of MEDELPHARM Science Lab to characterize radial die wall pressure powders with instrumented die.
MySTYL'One
April 22, 2022
MySTYL'One user exclusive!
New bulletin available on the methodology of MEDELPHARM Science Lab to study the effects of granulation critical process parameters on product quality attributes. A development of a new directcompression grade of excipient produced by granulation.
#STYL'One evo #compactibility #bulletin #powder granulation #pressure #carr index #angle of repose #flowability
MySTYL'One
June 17, 2021
MySTYL'One member exclusive!
MySTYL’One Live session is now available for replay.
Please click here to access the video (registered users only).
The video presents a joint experimental and numerical study from University of Bordeaux and Skyepharma’s research teams.
The webinar is extended with a hands-on demo on the STYL’One
Evo showing how to develop press-coated tablets.
MySTYL'One
March 4, 2021
On February 17th, Cedrine de Backere, PhD Student
from Ghent University (Belgium) presented her work on external lubrication and
how to mitigate the impact of lubricants on quality attributes. Bruno Leclercq,
MEDELPHARM’s Science Lab Head and Business Developer also presented innovations
from MEDELPHARM
on external lubrication. The session ended with a Q&A.
For those who could not join us you can freely access the
transcript below.
Note: the registered members of MySTYL’One can access the full video of the webinar HERE.