MySTYL'One
March 13, 2023
In this paper you will find a study that focuses on the assessment of the capping problem using computer modelling of the pharmaceutical powder compression and consolidation process using the finite element analysis (FEA) method implementing the Drucker–Prager Cap (DPC) model. The paper is available in the PAPERS section.
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In this paper you will find a study that focuses on the assessment of the capping problem using computer modelling of the pharmaceutical powder compression and consolidation process using the finite element analysis (FEA) method implementing the Drucker–Prager Cap (DPC) model. The paper is available in the PAPERS section.
Find others papers here and learn about
#STYL'One #Powder compaction #Drucker-Prager Cap model #capping
Medelpharm
Jan. 18, 2023
MySTYL'One members exclusive!
can be challenging, due to the multiple competing technological aims, such as flow, compactability, lubrication and drug release. Tablets are complex and, whether due to ignorance or indeterminacy, uncertainty also makes it difficult to develop tablets robust enough to cope with scale-up and Production. Speed sensitivity of the compression mix can come as an unwelcome surprise to those who did not know that tablets have...
MySTYL'One members exclusive!
can be challenging, due to the multiple competing technological aims, such as flow, compactability, lubrication and drug release. Tablets are complex and, whether due to ignorance or indeterminacy, uncertainty also makes it difficult to develop tablets robust enough to cope with scale-up and Production. Speed sensitivity of the compression mix can come as an unwelcome surprise to those who did not know that tablets have speed limits! Speed sensitivity may also be called strain rate sensitivity. The penalty for exceeding the speed limit is capping, making tablet production impossible. During development capping/lamination is unacceptable for further progression.
#viscoelasticity #tablet development #scale-up #Quality by Design #capping
MySTYL'One
July 22, 2022
The present works demonstrated from a study to predict capping on biconvex tablets from a wide range of products (18 formulations, 8 of which presenting capping), using the properties characterized on defect-free flat-faced tablets (tensile strength, solid fraction, elastic recovery, etc.). The study is available in the PAPERS section.
Find others papers here and learn about
The present works demonstrated from a study to predict capping on biconvex tablets from a wide range of products (18 formulations, 8 of which presenting capping), using the properties characterized on defect-free flat-faced tablets (tensile strength, solid fraction, elastic recovery, etc.). The study is available in the PAPERS section.
Find others papers here and learn about
MySTYL'One
June 20, 2022
The present work details the influence of the unloading step on capping using a compaction simulator. Full paper available in the PAPERS section.
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Vincent Mazel - University of Bordeaux
May 15, 2021
MySTYL'One members exclusive!
Watch the replay of the presentation delivered by Vincent Mazel (user of a STYL'One Evolution, University of Bordeaux, France) during the 12th APV PBP World meeting.
#video #capping #lamination #study #university of Bordeaux #unloading #webinar