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    Mimicking dry granulation on the STYL'One Evo to improve flowability

    Mimicking dry granulation on the STYL'One Evo to improve flowability

    Bulletins - 16/04/2024 - by Sixtine Caquant, Adrien Pelloux
    Dry granulation is a commonly used process in the pharmaceutical industry. It provides several key advantages, including precise particle size control, improved flowability of powders, versatility in processing materials, increased …
    pilules-bocal-verre

    Emerging Trends And Challenges For Pharmaceutical Production

    Newsfeeds - 15/04/2024 -
    The global pharmaceutical market, valued at around 1.25 trillion USD, is expected to grow steadily, with the United States leading in revenue generation. Despite the COVID-19 pandemic, pharmaceutical supply chains …
    Image Fabrication and Optimization of Directly Compressible Self-Emulsifying Tablets Containing Cannabis Extract Obtained from Supercritical Carbon Dioxide Extraction

    Fabrication and Optimization of Directly Compressible Self-Emulsifying Tablets Containing Cannabis Extract Obtained from Supercritical Carbon Dioxide Extraction

    Newsfeeds - 15/04/2024 -
    The text discusses the challenges of low bioavailability of Tetrahydrocannabinol (THC) and Cannabidiol (CBD) in orally administered cannabis extract due to first-pass metabolism. It explores the use of a self-emulsifying …
    Nano_on_table_transparent

    AustinPx Invests in Pharmaceutics and Manufacturing Capabilities to Accelerate Drug Development

    Newsfeeds - 11/04/2024 -
    AustinPx, a prominent contract development and manufacturing organization (CDMO) focusing on enhancing the bioavailability of orally delivered small molecule drug candidates, has announced the acquisition of cutting-edge equipment to bolster …
    no-image

    Modeling of STYL'One Evolution correction factors for multicomponent mixtures scaling-up to roller compaction

    Papers - 11/04/2024 - by Fabia Arpago, Agostino Dall'Ara
    Roll compaction (RC) stands as a cost-efficient dry granulation technique extensively utilized in the pharmaceutical sector. In the initial stages of formulation development, particularly when resources are constrained, the ability …
    Image Hot-Melt extrusion - from theory to application in pharmaceutical formulation - where are we now

    Hot-Melt Extrusion: from Theory to Application in Pharmaceutical Formulation – Where Are We Now?

    Newsfeeds - 10/04/2024 -
    Hot-melt extrusion (HME) stands as a widely acknowledged and robust technology, effectively enhancing the bioavailability of poorly soluble active pharmaceutical ingredients while offering an efficient continuous manufacturing process. The twin-screw …
    Image Right from the start Designing advanceable formulations and processes at phase 1

    Right from the start: Designing Advanceable Formulations and Processes at Phase I

    Newsfeeds - 09/04/2024 -
    The text discusses the importance of designing drug formulations and processes that are advanceable from the early stages of development, emphasizing safety, efficacy, manufacturability, and commercial viability. It highlights the …
    Image Rapid And Material-Sparing Feasibility Screening For Hot Melt Extrusion

    Rapid And Material-Sparing Feasibility Screening For Hot Melt Extrusion

    Newsfeeds - 05/04/2024 -
    Amorphous solid dispersions (ASD) present a solution for enhancing the bioavailability of crystalline APIs that are otherwise poorly soluble. Two primary methods for manufacturing ASDs are spray drying and hot …
    Illustration article Interphex

    KORSCH America highlights latest tableting technology during Interphex 2024

    Newsfeeds - 03/04/2024 -
    KORSCH America Inc., division of KORSCH AG., a leading name in the pharmaceutical equipment manufacturing industry, is preparing its participation at Interphex in New York. Scheduled from April 16th to …
    Image KORSCH X 5 Contract Pharma

    KORSCH to Introduce Advanced X 5 Tablet Press at INTERPHEX

    Newsfeeds - 02/04/2024 -
    KORSCH America, the U.S. subsidiary of KORSCH AG, will unveil its latest tablet press, the X 5, at INTERPHEX in New York City. This innovative single-sided rotary press offers increased …
    Image Impact testing as a new approach to determine mechanical strength of pharmaceutical tablets

    Impact testing as a new approach to determine mechanical strength of pharmaceutical tablets

    Newsfeeds - 02/04/2024 -
    The paper discusses shortcomings in traditional standardized testing methods for determining tablet strength in the pharmaceutical industry, particularly focusing on the tablet breaking force test and friability test. These methods …
    Illustration systems engineering for high containment

    Systems engineering for high containment

    White Papers - 27/03/2024 - by Johannes Nitzsche
    Planning a fully integrated tablet compression system for high-containment requires extensive know-how and experience. “Not only is the tablet press itself affected by the more stringent safety precautions at each …