April 14, 2022

Advantages of Mannitol in Pharmaceutical Granulation Processes - A Comparison of Different Polymorphic Forms

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New bulletin available on binding and tableting properties standard crystallized mannitol in β-polymorphic form for use with wet granulation. A comparison of different polymorphic forms.

#bulletin #Dwell Time #viscoelasticity #viscoplasticity #compression profiling

March 21, 2022

Using a Model-based Material Sparing Approach for Formulation and Process Development of a Roller Compacted Drug Product

The present work details a material sparing approach that combines material profiling with Instron uniaxial die-punch tester and use of a roller compaction mathematical model to guide both formulation and process development of a roller-compacted drug product.

Find others Papers section and learn about

• Recent Progress in Roll Compaction Process Development for Pharmaceutical Solid Dosage Form Manufacture
• Efficient development of sorafenib tablets with improved oral bioavailability enabled by coprecipitated amorphous solid dispersion
• Roller Compaction Scale-Up Made Simple: An Approximate Analytical Solution to Johanson's Rolling Theory

#Roller compaction #compression profiling #scale-up batches #drug product