Keep up with the latest in the tableting community!
June 15, 2021
A new paper published by the university of Düsseldorf on the compression of Metformin Hydrochloride, a drug which had before not been directly compressed. However using a quasi-emulsion solvent-diffusion (QESD) crystallization technique allows for better flowability and reduce storage agglomeration, making direct compression possible after evaluating the tabletability of the material.
Full paper available here.
Oct. 30, 2020
Read the article from Catalent explaining the 3 known technologies to develop tablets:
- direct compression
- wet granulation
- dry granulation,
with a focus on roller compaction, as it remains an effective solution for most APIs, in particular those as amorphous solid dispersions.
July 10, 2020
In this explanatory video Merck compares 3 possibilities for tableting: direct compression, wet granulation and roller compaction/dry granulation, including explanations on the processes and pros & cons of each.