April 4, 2022

Pharmaceutical Development of Film-Coated Mini-Tablets with Losartan Potassium for Epidermolysis Bullosa

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The present work details the development of an oral solid dosage form to address the rare disease epidermolysis bullosa, which can appear already in newborn children. Full paper available in the PAPERS section.

Find others papers here and learn about

• Transfer and scale-up of the manufacturing of orodispersible mini-tablets from a compaction simulator to an industrial rotary tablet press
  
• QbD approach formulation design for metformin HCI and evaluations
  
• Tableting of mini-tablets in comparison with conventionally sized tablets: A comparison of tableting properties and tablet dimensions
  

#STYL'One #stability #epidermolysis bullosa #losartan potassium #dry granulation #paediatrics #rare disease #mini-tablets #coating

Oct. 30, 2020

Roller compaction: new trends, challenges and solutions

Read the article from Catalent explaining the 3 known technologies to develop tablets:

- direct compression
- wet granulation
- dry granulation, 

with a focus on roller compaction, as it remains an effective solution for most APIs, in particular those as amorphous solid dispersions.

#direct compression #dry granulation #Roller compaction #wet granulation