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Showing posts tagged as : #granulation

Feature article

Bruno Villa

Sept. 10, 2021

Dry Granulation a material sparing method

WHY IS DRY GRANULATION SO POPULAR THESE DAYS?

Granulation of pharmaceutical powder is often required to prevent segregation of the Active Pharmaceutical Ingredient (API) and/or to enhance the blend flowability, which is critical to ensure consistent tablet mass (weight) on rotary tablet presses. Dry granulation has been known for decades. The main benefit is a lower cost of operation compared to wet granulation. But most interestingly, it’s much easier to contain a roller compactor to process high potent drugs. It’s also a truly continuous process, which is a big trend these days. One have to point out that in the past decade, equipment manufacturers have introduced more instrumentation and advanced control systems, such as Gerteis or LB Bohle to name a few, allowing a more consistent density on the ribbons through a gap control loop system

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