MEDELPHARM
May 3, 2021
There are numerous tablet defects: chipping, picking & sticking, cracking, lamination & capping to name a few.
Lamination & capping often occur during scale-up and are main issues in our industry. Capping is the partial or complete removal of the crown of a tablet from the main body, while lamination is the separation of a tablet into two or more distinct layers. However, those 2 phenomenon share similar causes...
MEDELPHARM
March 23, 2021
Reducing “time to market” is the ultimate goal
for every pharmaceutical lab. Being the first on
the market brings a competitive advantage for
prescription, over-the-counter, or generic-drug
manufacturers. Applying quality-by-design
(QbD) principles at the formulation phase can
prevent tablet defects at an early stage and
thereby drastically reduce time during the
complex and troublesome phase of “scale-up”.