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Showing posts tagged as : #troubleshooting

Feature article

MEDELPHARM

May 3, 2021

Troubleshooting tablet defects in no-time

There are numerous tablet defects: chipping, picking & sticking, cracking, lamination & capping to name a few.

Lamination & capping often occur during scale-up and are main issues in our industry. Capping is the partial or complete removal of the crown of a tablet from the main body, while lamination is the separation of a tablet into two or more distinct layers. However, those 2 phenomenon share similar causes...

#troubleshooting #deffect #tablet

Feature article

MEDELPHARM

March 23, 2021

A QbD approach to shorten tablets development time

Reducing “time to market” is the ultimate goal for every pharmaceutical lab. Being the first on the market brings a competitive advantage for prescription, over-the-counter, or generic-drug manufacturers. Applying quality-by-design (QbD) principles at the formulation phase can prevent tablet defects at an early stage and thereby drastically reduce time during the complex and troublesome phase of “scale-up”.

#troubleshooting #QbD #development

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