CMAC's Digital Medicines Manufacturing
March 21, 2023
March 21st, 3.30pm (GMT)
"From particles to drug product performance and stability"
In this webinar, we will discuss the interplay between particle properties, formulation, microstructure and stability-related performance changes. We will demonstrate the integrated use of advanced measurement techniques with multi-scale modelling approaches to gain insights into the relationship between particle characteristics, compact microstructure, storage conditions and the disintegration and dissolution performance of tablets. The new insights gained about the relationship between the raw material attributes, manufacturing process and drug product performance will allow us to move away from a laborious and lengthy empirical, trial and error, development to a digitally driven design process, where the tablet disintegrates and releases the drug substance in a reproducible and predictable manner.