Characterization of tableting speed-dependent deformation properties of active pharmaceutical ingredients in powder mixtures using out-of-die method
Press review
MySTYL'One
Jan. 9, 2022
The paper highlights an evaluation method to determine the effect of speed during tableting on the compression properties of pharmaceutical powders (APIs mixed with excipients).
Different tests were conducted to determine viscoelasticity, stress relaxation, followed by compaction on both STYL’One compaction simulator and a rotary press. Results show that the sensitivity of the out-of-die SRS was higher than that of in-die SRS.
Full results available in the paper, head to
the “Papers” section of MySTYL'One (members only).
#scale-up #viscoelasticity #'strain rate sensitivity' #'tableting speed' #'out-of-die' #'compression'