Using a Model-based Material Sparing Approach for Formulation and Process Development of a Roller Compacted Drug Product

The present work details a material sparing approach that combines material profiling with Instron uniaxial die-punch tester and use of a roller compaction mathematical model to guide both formulation and process development of a roller-compacted drug product.

Find others Papers section and learn about

• Recent Progress in Roll Compaction Process Development for Pharmaceutical Solid Dosage Form Manufacture
• Efficient development of sorafenib tablets with improved oral bioavailability enabled by coprecipitated amorphous solid dispersion
• Roller Compaction Scale-Up Made Simple: An Approximate Analytical Solution to Johanson's Rolling Theory